Stem Cell Therapy aids in returning the bodies immune system to normal functional state and a drastic reduction in the patient’s inflammatory markers. This anti-inflammatory effect may last for years leading to ease in pain and faster recovery.
Stem Cells have the unique ability to regulate the immune system by increasing our regulatory T cells. This allows our system to halt pathological responses while preserving its ability to fight disease. After therapy, most patients will have a decrease in pro-inflammatory markers TNF‐α and IL-6, and most importantly the benefit of feeling well
In addition, to regulating the immune system, stem cell therapy may help with healing and recovery. Most importantly, it has been shown to have no serious adverse effects.
The immune system is naturally complex, with many components ultimately working together to maintain and regulate our blood system. All diseses have a direct correlation with immune dysfunction. One of the immune systems main function is to protect the body from attack of foreign pathogens and toxins. The capacity to distinguish between “self” and “non-self” substances plays a central role in the process of immunity[2,3]: autoimmune disorders are the result of the breakdown of this self-tolerance.
The pharmacologic options for autoimmune disorders are mainly based on immunosuppressive activities that minimize or delay cellular damages in the affected organs rather than regulating or controlling the autoimmune process[2,5].
Studies have shown the potential of MSCs in treating autoimmune disorders. MSCs can be used as a treatment modality to regulate the immune system based on their properties . MSCs secrete molecules that can control the T cell response by increasing the amount of regultory T cells circulating in our body. These molecules secreted by MSCs also inhibit proliferation and function of cytotoxic T cells, natural killer cells, and B cells which could potentially prevent priming of naive T cells needed to initiate autoimmune diseases [6,10-12]. The dynamic secretion pattern and the immunomodulatory properties of MSCs make these cells phenomenal candidates for the treatment of many different autoimmune diseases.
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